Hög risk att insjukna i tyreotoxikos i norra Sverige. Retrospektiv genomgång av journaler i Norrbotten för åren 2004-2005
Engelsk titel: High risk of thyrotoxicosis in Northern Sweden. Retrospective survey of medical records for 2004-2005 in Norrbothnia
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Författare:
Westerlund E
;
Eliasson M
Email: ellen.westerlund@gmail.com
Språk: Swe
Antal referenser: 13
Dokumenttyp:
Artikel
UI-nummer: 08111378
Sammanfattning
There are few studies on the incidence of thyrotoxicosis and none at all covering the last ten years. Earlier surveys differ widely regarding risk and type of thyrotoxicosis. To study the age-specific incidence and type of thyrotoxicosis in adults in the county of Norrbothnia, in the farthest north of Sweden. Retrospective analysis of case records from all primary care health centres and medical departments during 2004 and 2005 with a catchement population of 200,000. Hyperthyroidism due to thyroiditis, interference in the analysis of thyroxin, factitia, or due to treatment with amiodarone or interferon were excluded. The total incidence of thyrotoxicosis in adults was 47/100,000/year, 76 in women and 18 in men. The incidence of Graves´disease was 28/100,000/year, 46 and 11, in women and men, respectively. For uninodular toxicosis the total incidence was 3/100,000/year, for multinodular 17 and for undefined toxicosis 9. Among subjects with Graves´ toxicosis, recurrent disease was common and 22 percent of female subjects and 32 percent of male subjects had previously been treated for thyrotoxicosis. The incidence of autoimmune toxicosis, excluding these persons, decreased to 39/100,000/year. Prevalence of current smoking was higher among incident cases of Graves´disease than in the general population. The incidence of thyrotoxicosis in northern Sweden is high but similar to studies from ten years ago from southern Sweden and Scotland. More than half of incident cases are autoimmune thyrotoxicosis which also is the dominant cause up to the age of 70 years.