Tobakksröyking og interaksjoner med legemidler
Engelsk titel: Tobacco smoking and drug interactions
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Författare:
Molden E
;
Spigset O
Email: espen.molden@farmasi.uio.no
Språk: Nor
Antal referenser: 11
Dokumenttyp:
Artikel
UI-nummer: 09031458
Sammanfattning
Tobacco smoking increases the turnover of many drugs due to induction of drug-metabolizing enzymes. Smokers therefore require higher doses of agents such as clozapine, olanzapine and theophylline than non- smokers. Enzyme induction declines after smoking cessation and without concomitant dose reduction there is an increased risk of adverse effects.