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Emphysematous pyelonephritis (EPN) is a rare, life-threatening infection of the kidney, characterized by production of gas within the renal parenchyma or perinephric tissue. Escherichia coli and Klebsiella are the most commonly isolated organisms. Most patients are diabetics. CT is diagnostic. Within half a year two patients with EPN were admitted. They were successfully treated with internal/percutaneous drainage (PCD), and antibiotics. Earlier, acute nephrectomy was first choice treatment, but recent studies point towards PCD and antibiotics as a better alternative.

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