Sök artiklar i SveMed+

Observera: SveMed+ upphör att uppdateras!



Metforminbehandling giver vedvarende laktatacidose efter hjertestop
Engelsk titel: Metformin treatment causes persisting lactic acidosis after cardiac arrest Läs online Författare: Gamst, Jacob ; Kjaersgaard Hansen, Lars ; Steen Rasmussen, Bodil Språk: Dan Antal referenser: 5 Dokumenttyp: Fallbeskrivning UI-nummer: 10121326

Tidskrift

Ugeskrift for Laeger 2010;172(49)3418-9 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Metformin associated lactic acidosis (MALA) is a rare condition with a prevalence of 3 per 100,000 patient-years. The reported mortality is about 50%. We describe a case of MALA in a 61- year-old obese, type II diabetic male who suffered a sudden cardiac arrest. After resuscitation, the patient developed severe lactic acidosis requiring continuous renal replacement therapy. The patient died within seven days from multiorgan failure. MALA should be suspected in therapy-resistant lactic acidosis. Haemofiltration/ haemodialysis will correct acidosis and clear metformin.