Multiple self-healing squamous epithelioma er en arvelig tilstand med selvhelende hudkraeft
Sammanfattning
Multiple self-healing squamous epithelioma - Ferguson-Smith disease (MSSE) is an autosomal dominant inherited disease with multiple, recurrent, histologically malignant tumours that undergo spontaneous regression. The gene for MSSE has recently been identified as the transforming growth factor-beta receptor 1 ( TGFBR1 ). Although rare, MSSE constitutes an important model of tumour-biology research. The discovery of the genetic background for MSSE paves the way for further elucidating the mechanisms involved in this peculiar self-healing cancer syndrome. Korrrespondance: Anne-Marie Gerdes , Klinisk Genetisk Afdeling, Rigshospitalet, Blegdamsvej 9, 2100 København Ø. E-mail: anne-marie.gerdes@rh.regionh.dk Antaget: 24. november 2011 Først på nettet: 30. januar 2011 Interessekonflikter: ingen