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Genetisk variation kan have betydning for udviklingen af kroniske postoperative smerter
Engelsk titel: Genetic variation may influence the development of persistent postsurgical pain Läs online Författare: Haunstrup Jeppesen, Maja ; Gögenur, Ismail Språk: Dan Antal referenser: 23 Dokumenttyp: Översikt UI-nummer: 15027774

Tidskrift

Ugeskrift for Laeger 2014;176(26)2484-8 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Persistent postsurgical pain is a major clinical problem. It is not fully understood why some patients develop persistent postsurgical pain while others do not. The genetic profile might play an important role in this development. In this article, we summarize the existing studies examining the effects of single nucleotide polymorphisms on the development of persistent postsurgical pain. The evidence in this area is sparse and the results are heterogeneous. Further studies are needed before firm conclusions can be made.