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Sammanfattning

Premature Ventricular Complexes (PVCs) are a highly prevalent phenomenon in everyday clinical practice. Nevertheless, the observation of PVCs is often met with uncertainty with regard to clinical significance, work-up, and indications as well as alternatives with regard to treatment. This clinical uncertainty is contrasted by the increasing insight in the fundamental mechanisms underlying PVCs. The task for the clinician is to separate the situations in which PVCs occurs as a benign phenomenon in an otherwise healthy individual, from the situations in which PVCs could indicate underlying cardiac disease, or even act a cause or trigger of such disease. This review introduces the reader to some of these insights from basic research, as well as clinical data, and the lack thereof that can guide clinical decision making when confronted with PVCs

MeSH