Flavonoid intake and the risk of age-related cataract in China’s Heilongjiang Province
Engelsk titel: Flavonoid intake and the risk of age-related cataract in China’s Heilongjiang Province
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Författare:
Ma, Yingna
;
Gao, Weiqi
;
Wu, Kun
;
Bao, Yongping
Email: y.bao@uea.ac.uk
Språk: Eng
Antal referenser: 49
Dokumenttyp:
Artikel
UI-nummer: 16023209
Sammanfattning
Background/objectives: Epidemiological evidence suggests that diets rich in flavonoids may
reduce the risk of
developing age-related cataract (ARC). Flavonoids are widely distributed in foods of plant origin, and
the
objective of this study was to evaluate retrospectively the association between the intakes of the five
flavonoid
subclasses and the risk of ARC.
Subjects/methods: A population-based case-control study (249 cases and 66 controls) was carried out
in
Heilongjiang province, which is located in the northeast of China, and where intakes and availability
of fresh
vegetables and fruits can be limited. Dietary data gathered by food-frequency questionnaire (FFQ)
were used
to calculate flavonoid intake. Adjusted odds ratio (OR) and 95% confidence interval (CI) were
estimated by
logistic regression.
Results: No linear associations between risk of developing ARC and intakes of total dietary
flavonoids,
anthocyanidins, flavon-3-ol, flavanone, total flavones or total flavonols were found, but quercetin and
isorhamnetin intake was inversely associated with ARC risk (OR 11.78, 95% CI: 1.6285.84, pB0.05,
and OR
6.99, 95% CI: 1.1243.44, pB0.05, quartile 4 vs. quartile 1, respectively).
Conclusion: As quercetin is contained in many plant foods and isorhamnetin in very few foods, we
concluded
that higher quercetin intake may be an important dietary factor in the reduction of the risk of ARC.