Continuous-mode 448 kHz capacitive resistive monopolar radiofrequency induces greater deep blood flow changes compared to pulsed mode shortwave: a crossover study in healthy adults
Engelsk titel: Continuous-mode 448 kHz capacitive resistive monopolar radiofrequency induces greater deep blood flow changes compared to pulsed mode shortwave: a crossover study in healthy adults
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Författare:
Kumaran, Binoy
;
Herbland, Anthony
;
Watson, Tim
Språk: Eng
Antal referenser: 41
Dokumenttyp:
Artikel
UI-nummer: 17110057
Sammanfattning
Aims: Radiofrequency-based electrophysical agents (EPAs) have been used in therapy practice over
several decades (e.g. shortwave therapies). Currently, there is insufficient evidence supporting such
EPAs operating below shortwave frequencies. This laboratory-based study investigated the deep
physiological effects of 448 kHz capacitive resistive monopolar radiofrequency (CRMRF) and compared
them to pulsed shortwave therapy (PSWT).
Methods: In a randomized crossover study, 17 healthy volunteers initially received four treatment conditions:
high, low and placebo dose conditions receiving 15-min CRMRF treatment and a control condition
receiving no intervention. Fifteen participants additionally received high-dose PSWT as fifth
condition, for comparison. Pre- and post-treatment measurements of deep blood flow and tissue
extensibility were obtained using Doppler ultrasound and sonoelastography. Group data were compared
using analysis of variance model. Statistical significance was set at p .05, 0.8 power, and 95%
confidence interval.
Results: Significant increases in volume and intensity of deep blood flow were obtained with CRMRF
over placebo, control (p ¼ .003) and PSWT (p < .001). No significant changes in blood flow velocity or
tissue extensibility were noted for any condition.
Conclusions: Deep blood flow changes with CRMRF were more pronounced than that with PSWT, placebo
or control. Potential greater therapeutic benefits need to be confirmed with comparative clinical
studies.