Engelsk titel: Congenital heart block - fetal risk beyond maternal antibodies
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Författare:
Wahren-Herlenius, Marie
Email: marie.wahren@ki.se
Språk: Eng
Antal referenser: 10
Dokumenttyp:
Artikel
UI-nummer: 18020318
Sammanfattning
During pregnancy, IgG is actively transported
over the placenta. In women
with rheumatic disease, such as primary
Sjögren’s syndrome, this will also
include IgG with autoreactive specificities.
When the pregnant woman carries
autoantibodies to the Ro/SSA antigens,
and more specifically the Ro52 protein,
there is a risk of the fetus developing a
congenital AV block.