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Personlig medicin nödvendiggör paradigmeskifte i evidensbegrebet
Engelsk titel: Personalised medicine requires a paradigm shift in the concept of evidence Läs online Författare: Nielsen, Ingolf ; Sigurd, Bjarne ; Örskov, Bjarne Språk: Dan Antal referenser: 14 Dokumenttyp: Översikt UI-nummer: 20030112

Tidskrift

Ugeskrift for Laeger 2019;181(23)2216-8 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Personalised medicine via a central biobank will require the introduction of a paradigm shift navigating by detecting pattern and correlation, instead of evidence of limited use in our complex environment. Accordingly, to make sense, population-wide data comprising “deep phenotype” including genetics, must be submitted to evaluation by “machine intelligence”, based on ”unsupervised learning” – the algorithm concomitantly improving its power with increasing mass of data. A system not based on deductive logic cannot be checked by logic but must be taken on face value.