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Utbrudd av infeksjon med multiresistent Acinetobacter baumannii
Engelsk titel: Outbreak of multiresistant Acinetobacter baumannii infection Läs online Författare: Onarheim H ; Höivik T ; Harthug S ; Digranes A ; Mylvaganam H ; Vindenes HA Språk: Nor Antal referenser: 21 Dokumenttyp: Fallbeskrivning UI-nummer: 00040635

Tidskrift

Tidsskrift for Den Norske Laegeforening 2000;120(9)1028-33 ISSN 0029-2001 E-ISSN 0807-7096 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

INTERPRETATION : Following discharge of the last patient and extensive cleaning and disinfection of the entire ward, the particularly resistant strain has not reoccurred. Still, this experience may warrant screening for multiresistant gram-negative rods in patients transferred from regions where broad resistance to antibiotics is a common problem. RESULTS : The ward was closed for admission of new patients and hygiene precautions were strengthened. Extensive testing of staff and equipment revealed multi-resistant A baumannii on a shower trolley shared by several patients. The outbreak strain was also identified by restriction endonuclease analysis. The patients were kept strictly isolated until their burn wounds were sufficiently healed to allow them to be discharged to their homes. MATERIALS AND METHODS : The outbreak strain was introduced from Alicante, Spain, by a transferred patient. This strain was resistant to all commonly available systemic antibiotics (including the karbapenems and all aminoglycosides), and sensitive only to polymyxin B. Two patients were critically ill, one of them died in septic shock. BACKGROUND : Nosocomial infections caused by multiresistant gram-negative bacteria represent an increasing problem, especially among intensive care patients. A serious outbreak of infection caused by multi-resistant Acinetobacter baumannii occurred in four burn patients. Acinetobacter is a gram-negative coccibacilli which is widespread in nature, and has been reported as an increasing problem in critically ill patients.