Engelsk titel: Diagnosis of depleted iron stores - do not use s-iron
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Författare:
Nödtvedt GM
;
Lövli OC
;
Åsberg A
Språk: Nor
Antal referenser: 14
Dokumenttyp:
Artikel
UI-nummer: 00067597
Sammanfattning
BACKGROUND : Analysis of s-ferritin is recommended for the diagnosis of depleted iron stores, but other parameters are still in use. The objective of this study was to determine the accuracy for s-iron, s-transferrin, transferrin saturation, b-hemoglobin and erythrocyte-MCH in diagnosing depleted iron stores.
MATERIAL AND METHODS : Data was collected from the Health Study of Nord-Trøndelag, 1995-1997. Blood samples from 3029 women aged 20-45 were analysed for iron status. In absence of bone marrow aspirate, s-ferritin was used as the standard for iron deficiency.
RESULTS : Highest diagnostic accuracy was found for s-transferrin. S-iron did not contribute with significant independent information.
INTERPRETATION : S-iron should not be used in the diagnosis of depleted iron stores.