Engelsk titel: High-resolution computer tomography in cystic fibrosis
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Författare:
Dorlöchter L
;
Röksund OD
;
Fluge G
;
Rosendahl K
Email: ludger.dorloechter@haukeland.no
Språk: Nor
Antal referenser: 16
Dokumenttyp:
Artikel
UI-nummer: 02071787
Sammanfattning
INTERPRETATION : High-resolution CT characterises very well the lung pathology in patients with cystic fibrosis. The degree of pathology assessed with a modified Bhalla score correlates well with forced expiratory volume in one second.
RESULTS : Mean high-resolution CT score was 8.0 (range 0-22). Bronchiectasis was found in 17 out of 21 patients, peribronchial wall thickening in 15 patients and mucous plugging in 14 patients. The Bhalla score showed a close correlation with forced expiratory volume in one second (r = -0.844, p < 0.01).
MATERIAL AND METHODS : We examined 21 patients (age 6-34) with high-resolution CT. The findings were scored using a modified Bhalla method, where score 0 is normal and score 27 reflects a maximal degree of e.g. bronchiectasis and mucous plugging.
BACKGROUND : Worsening lung disease is the most important factor concerning quality of life and survival rate in the approximately 250 patients with cystic fibrosis in Norway. Pulmonary high-resolution CT has been advocated as a precise diagnostic method, that offers the opportunity to detect slight disease progression.