Engelsk titel: Vitamin D and breast cancer
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Författare:
Rejnmark Nielsen L
;
Mosekilde L
Email: rejnmark@post6.tele.dk
Språk: Dan
Antal referenser: 0
Dokumenttyp:
Översikt
UI-nummer: 07041297
Sammanfattning
Active vitamin D increases the differentiation and exerts antiproliferative effects in cancer cells. Recent data suggest that vitamin D is activated locally in cancer cells. Ecologic studies have shown an inverse correlation between breast cancer mortality and sun exposure and dietary vitamin D intake. In clinical studies an impaired vitamin D status is association with a 20-30% increased breast cancer incidence and 10-20% increased mortality. As vitamin D insufficiency is common, it is important to clarify whether vitamin D status affects the risk and prognosis of breast cancer.