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Cerebral venetrombose - diagnostikk og behandling
Engelsk titel: Cerebral venous thrombosis - diagnosis and treatment Läs online Författare: Johnsen HJ ; Vorhaug A ; Kvistad KA Språk: Nor Antal referenser: 34 Dokumenttyp: Översikt UI-nummer: 07041449

Tidskrift

Tidsskrift for Den Norske Laegeforening 2007;127(8)1069-73 ISSN 0029-2001 E-ISSN 0807-7096 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

RESULTS AND INTERPRETATION : CVT is thought to be responsible for about 0.5-1.0% of all strokes. Headache is the initial symptom in 70-90% of the cases. Apart from this, symptoms vary considerably. CVT was previously assumed to be a rare condition with a high mortality, as the diagnosis could in effect only be made post mortem. Conditions with a benign course can now be diagnosed with modern neuroradiological examinations. All patients should be assessed carefully; particular attention should be given to possible congenital or acquired forms of thrombophilia. Scepsis about the use of anticoagulants in CVT has long prevailed, especially in connection with haemorrhagic infarcts. During the last 10-15 years, several studies indicate that anticoagulation with heparin, or low-molecular heparin, should be the initial treatment of choice. Catheter-based endovascular thrombolytic treatment should be considered in serious cases where anticoagulant treatment is unsuccessful. Mortality is about 10%. MATERIAL AND METHODS : This article is based on a review of relevant literature and on the authors' personal experience. BACKGROUND : Cerebral venous thrombosis (CVT) is a rare cause of stroke, and an important differential diagnosis for a number of neurological complaints. This review article concerns the aetiology, pathology, diagnostic work-up and treatment of the condition.