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Behandling af hormonrefraktaer metastatisk prostatacancer
Engelsk titel: Treatment of hormonal refractory metastatic prostate cancer Läs online Författare: Sengelöv L ; Klarskov OP ; Karlsson S Språk: Dan Antal referenser: 9 Dokumenttyp: Artikel UI-nummer: 07051632

Tidskrift

Ugeskrift for Laeger 2007;169(20)1905-7 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Hormonal refractory metastatic prostate cancer is a fatal disease with a poor prognosis. Treatment options are palliative with second line anti-hormonal, estrogens and prednisolon. When palliation is the goal, the side effects have to be carefully considered. Local radiotherapy has an effective pain relieving effect, and can be repeated. Chemotherapy with docetaxel and prednisolon is indicated in patients with symptomatic metastatic disease. Newer options with immunotherapy and designed molecules have not yet proven effective. Pain and anemia are significant symptoms and should be treated in a multidisciplinary setting.