Trening etter perkutan koronar intervensjon - en undervurdert behandlingsmulighet?
Engelsk titel: Training after percutaneous coronary intervention- an undervalued treatment option?
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Författare:
Munk PS
;
Larsen AI
Email: smpe@sus.no
Språk: Nor
Antal referenser: 29
Dokumenttyp:
Översikt
UI-nummer: 07051656
Sammanfattning
BACKGROUND : Even though regular exercise training after myocardial infarction reduces morbidity and mortality, training after percutaneous coronary intervention (PCI) is still not part of the standard treatment. This article reviews the documentation on exercise training with coronary artery disease and examines the effect on pathophysiological mechanisms that play an important role in the progression of coronary artery disease and restenosis after PCI with stent implantation.
MATERIAL AND METHODS : The article is based on a search in PubMed and the Cochcrane database.
RESULTS AND INTERPRETATION : The effect of regular exercise training on morbitity and mortality in coronary artery disease without myocardial infarction is not well documented. But the data indicate that training has an antiinflammatory effect in the vessel wall. Regular exercise training in these patients increases the bioavailibility of nitric oxide and is a non-pharmacological option to improve the endothelial function. Prospective, randomised, controlled trials are needed to evaluate whether there is a beneficial clinical effect of training after PCI treatment.