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Paranoia (delusional disorder) is an uncommon chronic condition, characterized by the presence of delusions and the relative absence of other psychopathology. Unlike in schizophrenia, the paranoiac delusions are nonbizarre and concern experiences that can conceivably occur, and the evidence mostly supports the hypothesis that paranoia is a distinct nosologic entity. The article reviews the epidemiology, pathogenesis, diagnosis, clinical manifestations and management of paranoia. It is concluded that further exploration is required and greater diagnostic and therapeutic attention needs to be given to the non-schizophrenic, non-affective, non-organic delusional psychoses.

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