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Vareniclin - et nyt middel til rygestop
Engelsk titel: Varenicline (Champix) - a new drug for smoking cessation Läs online Författare: Tönnesen P Språk: Dan Antal referenser: 9 Dokumenttyp: Artikel UI-nummer: 07121887

Tidskrift

Ugeskrift for Laeger 2007;169(47)4051-2 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Varenicline is a new drug for smoking cessation that reduces cravings by binding to the alfa4-beta2-nicotine-achethylcholine receptors in the brain (partial agonist). Varenicline for 12 weeks was found to be effective for smoking cessation and more effective than bupropionSR after 3 months. The adverse events were mild with transient nausea reported by less than one third of the subjects. Varenicline should be used for smoking cessation when nicotine replacement products have failed or are undesired.