Engelsk titel: Induction of spermatogenesis in hypogonadotrophic hypogonadism
Läs online
Författare:
Oldereid NB
;
Tanbo T
Email: nan.oldereid@rikshospitalet.no
Språk: Nor
Antal referenser: 17
Dokumenttyp:
Översikt
UI-nummer: 08021329
Sammanfattning
RESULTS AND INTERPRETATION : Hormonal regulation of the spermatogenesis involves complex interaction between structural elements (paracrine and endocrine) in the testicle and the endocrine system. Hormonal treatment of men with hypogonadotrophic hypogonadism comprises injections of gonadotrophins, administered by the patient in close cooperation with a specialist. It may be necessary to maintain this treatment for up to two years, but it is usually effective in initiating or restoring of spermatogenesis.
MATERIAL AND METHODS : The review is based on a recent literature survey and many years of clinical experience with infertile patients.
BACKGROUND : Reduced or missing sperm production is the main reason for infertility in a third of the couples who seek treatment. An uncommon cause of testicular failure is hypogonadotrophic hypogonadism. This review article discusses causes of this condition in men, medical treatment and prognosis with regard to fertility.