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Biologisk behandling af virus-hepatitis
Engelsk titel: Biological treatment of chronic viral hepatitis Läs online Författare: Pedersen C ; Ross Pedersen C Språk: Dan Antal referenser: 10 Dokumenttyp: Artikel UI-nummer: 08061242

Tidskrift

Ugeskrift for Laeger 2008;170(24)2137-40 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Interferon-alfa is used for the treatment of chronic viral hepatitis. The best results for HCV are obtained with pegylated interferon-alfa in combination with the antiviral drug ribavirin. Sustained response (cure) is obtained in 40% (genotype 1) to 85% (genotype 2 or 3) of treated patients. Interferon-alfa has many side effects, and the selection of patients for treatment should be made taking into consideration the individual prognosis and relative and absolute contraindications. New biologics are in clinical development.