Intrauterin blodtransfusion vid allvarlig erytrocytimmunisering. Nödvändigt, men inte riskfritt, ingrepp
Engelsk titel: Intrauterine blood transfusion in severe erythrocyte stimulation. A necessary intervention but not without risks
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Författare:
Engkvist F
;
Wåhlin M
;
Axelsson O
Email: frida.engkvist.6648@ student.uu.se
Språk: Swe
Antal referenser: 12
Dokumenttyp:
Artikel
UI-nummer: 08111415
Sammanfattning
We have identified 32 cases of intrauterine transfusions performed between 1984-2006 at the University Hospital in Uppsala. In total, 116 transfusions were performed, on average 3 per foetus. Most often, the blood was given in the umbilical vein at the placental insertion and the first transfusion was usually done at 25 weeks of gestation. The foetuses were severely or moderately anaemic prior to the first transfusion and at the following transfusions the Hb values were above the limit for severe anaemia. At delivery, a majority of the infants had Hb values above 100 g/l. Complications related to the transfusions occurred for 9 of the 32 cases. Most infants were delivered by elective caesarean section at the 33rd week of gestation and at birth they had high Apgar score, low birth weight and stayed, on average, one week on the neonatal ward. Thirty infants survived and were discharged in good health. Two infants died, one before and one after birth, the last case was with all probability a consequence of the transfusion procedure. Intrauterine transfusions are associated with a relatively high risk of complications but are, in many cases, a life saving procedure.