Engelsk titel: Development of tooth form, and sensory nerve supply are strictly coordinated
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Författare:
Kettunen P
;
Kvinnsland IH
;
Fristad I
;
Luukko K
Email: paivi.kettunen@biomed.uib.no
Språk: Nor
Antal referenser: 20
Dokumenttyp:
Artikel
UI-nummer: 09033278
Sammanfattning
To get a functional tooth, coordinated development of many anatomical structures and physiological systems is essential. Peripheral trigeminal sensory innervation is of high importance for the function and protection of the teeth. The development of the tooth innervation is intimately linked with advancing tooth formation. Recent molecular and genetic data have provided evidence that local epithelial-mesenchymal tissue interactions are part of the odontogenic signaling network that not only control the formation of the tooth organ proper but also the trigeminal axon navigation. Tissue interactions, thus, appear to provide the mechanisms to integrate formation of tooth shape and development of dental sensory innervation.