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Läkemedelsorsakad leverskada av kosttillskottet Fortodol. Manipulerat preparat försenade diagnos
Engelsk titel: Drug-induced liver injury from the dietary supplement Fortodol. A manipulated preparation delayed the diagnosis Läs online Författare: Kechagias, Stergios ; Hägg, Staffan ; Lofti, Kourosh Språk: Swe Antal referenser: 17 Dokumenttyp: Fallbeskrivning UI-nummer: 10021324

Tidskrift

Läkartidningen 2010;107(4)186-8 ISSN 0023-7205 E-ISSN 1652-7518 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Pharmaceutical preparations are serious contributors to liver disease. The diagnostic approach of drug-induced liver injury is difficult and requires a high degree of suspicion and the exclusion of alternative causes of liver damage. Adulteration of food supplements is a potential cause of serious hepatotoxicity. A case of severe jaundice after consumption of Fortodol, which according to the manufacturer contained the active substances turmeric and phenylalanine, is reported. Several months later more patients experiencing hepatotoxicity from Fortodol was reported and it was discovered that the toxicity was related to adulteration by nimesulide.