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Overlevelse hos voksne med akutt lymfoblastisk leukemi
Engelsk titel: Survival in adults with acute lymphoblastic leukaemia Läs online Författare: Tangen, Jon-Magnus ; Flöisand, Yngvar ; Haukås, Einar ; Naess, Inger Anne ; Skjeldbakken, Tove ; Stapnes, Camilla ; Tjönnfjord, Geir E Språk: Nor Antal referenser: 18 Dokumenttyp: Artikel UI-nummer: 10091763

Tidskrift

Tidsskrift for Den Norske Laegeforening 2010;130(17)1710-3 ISSN 0029-2001 E-ISSN 0807-7096 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

the Norwegian treatment protocol for acute lymphoblastic leukaemia in adults was introduced in 1982 and has undergone minor changes thereafter. Earlies studies from The South Eastern Norway Regional Health Authority have reported 50 % five-year overall survival in patients treated accroding to this protocol. This article presents survival data for Norwegian adults with acute lymphoblastic leukaemia on a national basis. Material and methods. Data for all patients between 15 and 65 years, who were diagnosed with acute lymphoblastic leukaemia in the period 2000 - 2007 according to The Norwegian Registry for Acute Leukaemia and Lymphoblastic Lymphoma, and were treated with chemotherapy with a curative intent were analysed for survival. Results. 128 patients were diagnosed with acute lymphoblastic leukaemia in the study period. The overall remission rate was 85.9 %. Five-year survival was 49.2 % overall, 31.4 % for patients 40 years or older and 62.6 % for those younger than 40 years. Interpretation. These results are in line with previous Norwegian studies and show a five- year overall survival which is more than 10 % higher than that reported in international multicenter studies. One explanation can be that the Norwegian treatment program is more intensive than most treatment protocols used in other countries.