Uppfattningen att "klamydia är en risk för klamydia" har styrkts. Risk för "återsmitta" kartlagd i prospektiv kohortstudie
Sammanfattning
A prospective cohort study with follow-up 6-8 months after inclusion was performed in order to estimate the risk for repeat infection with Chlamydia trachomatis among 20-39 years old STI-clinic attendees in Stockholm. Data collection consisted of self-sampled vaginal and urine specimens analyzed by Becton Dickinson ProbeTec™-method, in-house tests for the new variant of Ct (nvCT), tests of cure and contact tracing results. 2814 visitors participated, 54% men, 10.8% Ct-positive at inclusion, 25.8% nvCT. The follow-up visit was attended by 49.9% and 2.4% were Ct-positive, 4.1% among participants positives at inclusion, 9.7% nvCT. A Ct-positive test at inclusion indicated a higher risk of Ct-positivity at follow-up and a self-reported Ct infection in the past increased the risk for a new Ct infection at inclusion, RR 1.3. Among index patients (IP) 3.2 sexual contacts and 0.7 Ct-positive contacts per IP were found. Tests of cure and contact tracing is likely to have contributed to the relatively low prevalence of Ct at follow-up compared to findings in a review of similar cohort studies.