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Autoimmun neutropeni i barnealderen
Engelsk titel: Autoimmune neutropenia in children Läs online Författare: Debois Kölbaek, Merete ; Windelborg, Bent ; Nielsen, Kaspar Rene Språk: Dan Antal referenser: 5 Dokumenttyp: Fallbeskrivning UI-nummer: 11117685

Tidskrift

Ugeskrift for Laeger 2011;173(46)2957-9 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Case reports of three children with autoimmune neutropenia are presented. The children had a number of infections, which required antibiotic treatment, mostly respiratory tract infections, but one child had a septic coxitis. During a follow-up period of 1-3 years, only one patient showed complete remission after 15 months of neutropenia. One child was treated with granulocyte colony-stimulating factor without effect, whereas two children received prophylactic antibiotics with clinical benefit. In view of the frequent infections and benefit of prophylactic measures, children with neutropenia or an inappropriately low neutrophil count during bacterial infections should be evaluated for autoimmune neutropenia.