Undertrycksbehandling av sår. Kunskap om verkningsmekanismer och komplikationer ger nya möjligheter
Sammanfattning
Negative pressure wound therapy (NPWT) creates a moist wound healing environment, drains wound exudate, reduces tissue edema, contracts the wound edges and mechanically stimulates the wound bed, and influences the blood perfusion of the wound edge, leading to angiogenesis and the formation of granulation tissue. The therapy can be targeted for a specific wound type by means of the negative pressure level, the choice of wound filler material (foam or gauze) and the way in which the negative pressure is applied (continuously, intermittently or variably). This article summarizes recent evidence regarding the biological effects of NPWT and suggests ways to tailor the therapy for specific wound types.