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Hög överlevnad hos nyfödda med kongenitalt diafragmabråck. 20 års uppföljning av patienter som vårdats i Stockholm
Engelsk titel: High survival rate among newborns with congenital diaphragmatic hernia. 20-year follow up of patients treated in Stockholm Läs online Författare: Burgos, Carmen Mesas ; Öst, Elin ; Wannberg, Marcus ; Frenckner, Björn Språk: Swe Antal referenser: 55 Dokumenttyp: Artikel UI-nummer: 12021605

Tidskrift

Läkartidningen 2012;109(6)287-91 ISSN 0023-7205 E-ISSN 1652-7518 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Since 1990 the treatment of congenital diaphragmatic hernia (CDH) in Stockholm has been characterized by gentle ventilation, preoperative stabilization, ECMO according to conventional criteria and delayed surgery. A second run of ECMO was offered if necessary. During the 20-year period 1990–2009 194 patients with CDH were admitted. 184 of these were Swedish with Swedish identification number and were eligible for long-term follow-up. 85 % of the patients were discharged alive. Long-term survival after 1–20 years was 79 %. Survival to discharge among ECMO patients was 69 % and 56 % had survived after 1–20 years. 13 patients required a second ECMO run. 8 of these survived to discharge and 7 were long-term survivors. We conclude that both survival to discharge and long-term survival are excellent in an international comparison with the presented treatment strategy. To further improve results on a national basis in Sweden centralization of care is suggested.