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Nya utsikter för kurativ strålbehandling av lokalt avancerad cancer
Engelsk titel: New prospects for curative radiotherapy of local advanced prostatic cancer Läs online Författare: Nilsson, Sten ; Castellanos, Enrique Språk: Swe Antal referenser: 20 Dokumenttyp: Översikt UI-nummer: 12021683

Tidskrift

Läkartidningen 2012;109(8)412-5 ISSN 0023-7205 E-ISSN 1652-7518 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

The development of radiotherapy for prostate cancer has been very rapid during the last few years. Modern conformal techniques have enabled reduced radiation to organs at risk and, as a consequence, less side-effects. Modern techniques have also made dose-escalation to the prostate possible. Local recurrences within treated volumes are therefore nowadays a rare phenomenon. Curative radiotherapy in combination with endocrine therapy results in superior overall survival as compared to endocrine therapy alone. Similarly, adjuvant radiotherapy results in increased overall survival after non-radical prostatectomy. Increased knowledge with respect to radiobiological characteristics of prostate cancer has led to new promising treatment concepts such as hypofractionation.