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Det kliniske forlöb ved valproatforgiftning hos en treårig
Engelsk titel: The clinical course of a three year-old girl after overdose of valproic acid Läs online Författare: Blicher, Thalia Marie ; Vestergaard, Esben Thöyssen ; Dalhoff, Kim Peder Språk: Dan Antal referenser: 5 Dokumenttyp: Fallbeskrivning UI-nummer: 12051918

Tidskrift

Ugeskrift for Laeger 2012;174(17)1165-6 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Valproic acid (VA) is an antiepileptic drug, and frequently prescribed in pediatrics. VA overdose results in central nervous system depression, insufficient respiration, tachycardia, hypotension, hepatotoxicity, and electrolyte derangement. We describe the clinical course of a three year-old girl after accidental intake of 6,000 mg VA. Treatment included activated charcoal. Clinical observation included measurements of blood pressure, cardiac telemetry, and measurements of serum VA and metabolic parameters every 4-6 hrs. The girl was discharged successfully after 72 hrs with her usual dose of VA.