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Fatal Clostridium sordellii-infektion udgået fra ovariecyste
Engelsk titel: Fatal Clostridium sordellii infection originated in an ovarian cyst Läs online Författare: Bjerregaard, Jens Holst ; Bulow, Charlotte ; Holler, Jon Gitz Språk: Dan Antal referenser: 5 Dokumenttyp: Fallbeskrivning UI-nummer: 12051966

Tidskrift

Ugeskrift for Laeger 2012;174(18)1231-2 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Clostridium sordellii is a Gram-positive bacterium which can cause a serious toxic shock syndrome with a mortality of up to 69%. C. sordellii is a part of the normal vaginal flora in up to 10% of all women. This case describes a fatal case of a healthy 49 year-old woman with a C. sordellii- infection originating from an ovarian cyst. Quick diagnosis is difficult because of the non-specific flu-like symptoms. Survival requires immediate source control and specific antibiotic therapy capable of suppressing toxin production. In rodents superantigen antibodies have shown neutralizing effects.