Sök artiklar i SveMed+

Observera: SveMed+ upphör att uppdateras!



Eruptiva nevi efter injektion av preparat marknadsfört som melanotan II. De två första svenska fallen beskrivs
Engelsk titel: Eruptive nevi after injection of drugs marketed as melanotan II. The first two Swedish cases described Läs online Författare: Burian, Ewa ; Burian, Elzbieta Språk: Swe Antal referenser: 16 Dokumenttyp: Fallbeskrivning UI-nummer: 13037008

Tidskrift

Läkartidningen 2013;110(5)208-10 ISSN 0023-7205 E-ISSN 1652-7518 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

The uncontrolled and unlicensed use of products labelled as melanotan I and II, increase skin pigmentation by imitating alpha-MSH (alpha-melanocyte stimulating hormone). These preparations are easily accessible on the internet and are self-administered by subcutaneous injections. We present the first two Swedish cases of eruptive nevi after injections of substances distributed as melanotan II. Multiple new nevi evolved in both patients after short use. Pre-existing nevi also became larger and darker in both cases. On examination all nevi appeared abnormally dark. After removal of one nevus in each patient, histology confirmed dysplastic features. After melanotan II use was discontinued, all nevi faded more or less in both cases while an additional nevus from one of the patients had to be removed. It was histologically confirmed as dysplastic. Physicians should be aware that these chemicals can complicate the clinical appearance of nevi, and advice against the use should be given.