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Muligt klinisk potentiale ved revertering af neuromuskulaer blokade med sugammadex ved anaestesi og kirurgi
Engelsk titel: Possible clinical potential in reverting muscular block with sugammadex in anaesthesia and surgery Läs online Författare: Öberg, Emilie ; Claudius, Casper Språk: Dan Antal referenser: 24 Dokumenttyp: Översikt UI-nummer: 13047145

Tidskrift

Ugeskrift for Laeger 2013;175(7)428-32 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Neuromuscular blockers (NMBs) provide good conditions for endotracheal intubation and surgery. NMBs have been associated with higher morbidity and mortality, mainly due to postoperative residual neuromuscular block. This may become history with the advent of sugammadex - an antidote to the NMB rocuronium - which within 1-3 minutes neutralizes the effects of rocuronium. High-dose rocuronium is now an alternative to suxamethonium in acute or short procedures and in a situation, where ventilation/intubating cannot be performed, sugammadex can reverse the rocuronium blockade within minutes.