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Dapsoninduceret fald i HbA 1c kan give et falskt billede af diabeteskontrollen
Engelsk titel: Dapsone-induced decrease in the HbA 1c level may cause artefacts in diabetic control Läs online Författare: Lajlev, Siv Elisabeth ; Ladefoged, Sören Andreas ; Hermansen, Kjeld Språk: Dan Antal referenser: 5 Dokumenttyp: Fallbeskrivning UI-nummer: 13047160

Tidskrift

Ugeskrift for Laeger 2013;175(8)505-6 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Glycated haemoglobin (HbA 1c ) is used to monitor glycaemic control in diabetic patients, and has recently been included as a diagnostic factor for type 2 diabetes mellitus (DM). A 50-year-old male with well-controlled type 1 DM, Mb Addison and coeliac disease was diagnosed with dermatitis herpetiformis and treated with dapsone. Subsequently, the patient presented a pronounced drop in HbA 1c without changes in blood glucose levels. S-fructosamine was in agreement with the previous stable HbA 1c values. Blood analyses showed inappropriately low HbA 1c values due to mild haemolysis and shortening of erythrocyte lifetime without anaemia.