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Diagnostik og behandling af Wernicke-Korsakovs syndrom hos alkoholmisbrugere kan optimeres
Engelsk titel: Diagnostics and treatment of Wernicke-Korsakoff syndrome patients with an alcohol abuse Läs online Författare: Nilsson, Maria ; Sonne, Charlotte Språk: Dan Antal referenser: 17 Dokumenttyp: Översikt UI-nummer: 13067401

Tidskrift

Ugeskrift for Laeger 2013;175(14)942-4 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Wernicke-Korsakoff syndrome is a condition with high morbidity and mortality and occurs as a consequence of thiamine defi­ciency. Clinical symptoms are often ambiguous and post-mor­tem examinations show that the syndrome is under­diagnosed and probably undertreated. There is sparse clinical evidence concerning optimal dosage and duration of treatment. This article reviews the current literature and concludes that all patients with a history of alcohol abuse should be treated with high dosage i.v thiamine for an extended period of time, albeit further research is needed.