NSAID er sjaeldent indiceret ved reumatoid artritis - gennemgang af et Cochranereview
Engelsk titel: Use of NSAIDs in rheumatoid arthritis should be limited
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Författare:
Lindberg, Mats
Email: mli@dadlnet.dk
Språk: Dan
Antal referenser: 10
Dokumenttyp:
Kommentar
UI-nummer: 13067428
Sammanfattning
In a Cochrane review the safety of non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin in people receiving methotrexate (MTX) for rheumatoid arthritis was evaluated. A total of 17 publications were analyzed. Concurrent use anti-inflammatory doses of aspirin with MTX were associated with renal and hepatic side effects, whereas NSAIDs appeared to be safe. Nevertheless there are well-known gastrointestinal, cardiovascular and renal side effects from NSAIDs. In my opinion, use of NSAIDs in rheumatoid arthritis should be limited, as there are better and less risky alternatives.