Fjerdegenerations-p-piller medförer större risiko for venös tromboemboli end andengenerations-p-piller
Engelsk titel: Fourth generation oral contraceptives are associated with a higher risk of venous thromboembolism compared to second generation
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Författare:
Krogh, Marlene Lunddal
;
Klindt Poulsen, Birgitte
Email: marlenelunddalkrogh@gmail.com
Språk: Dan
Antal referenser: 28
Dokumenttyp:
Översikt
UI-nummer: 13077584
Sammanfattning
It has been widely discussed whether fourth generation oral contraceptives (OC) are associated with a higher risk of venous thromboembolism (VTE) compared to second generation. Lack of randomized controlled trials, methodological problems and inconsistent criteria for the VTE event has led to conflicting results. Three newly published studies utilising improved methodology show that fourth generation OC are associated with an increased risk of VTE compared to second generation OC. This knowledge has led to a change in recommendation of the first drug of choice, which is now second generation OC.