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Nya behandlingsmöjligheter vid vaskulärt Ehlers-Danlos syndrom
Engelsk titel: New treatment options for vascular Ehlers-Danlos syndrome Läs online Författare: Björck, Martin ; Hägg, Anders ; Wanhainen, Anders ; Hellström Pigg, Maritta ; Bergqvist, David Språk: Swe Antal referenser: 15 Dokumenttyp: Artikel UI-nummer: 13087733

Tidskrift

Läkartidningen 2013;110(29-31)1354-5 ISSN 0023-7205 E-ISSN 1652-7518 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Vascular Ehlers-Danlos’ Syndrome is a rare genetic disorder affecting procollagen type III, affecting approximately 50 individuals in Sweden. In this article recent advances in the treatment of the disease are summarized. Prophylaxis against vascular catastrophies can be performed with the specifically well designed betablocker celiprolol, and preliminary experiences of this treatment are reported. When arterial dissections and aneurysms develop, both open and endovascular surgery can be considered, but serious complications are common, and conservative management is the first option. It is important that the first line of treatment is decentralized, but in close collaboration with a dedicated academic unit.