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Forhöjet alaninaminotransferase hos en fireårig pige som tidligt tegn på autoimmun hepatitis
Engelsk titel: Elevated alanine aminotransferase in a four-year-old girl as an early sign of autoimmune hepatitis Läs online Författare: Hörby Jörgensen, Marianne ; Brix Christensen, Vibeke ; Clemmesen, Otto Språk: Dan Antal referenser: 3 Dokumenttyp: Fallbeskrivning UI-nummer: 14047881

Tidskrift

Ugeskrift for Laeger 2014;176(8)753-4 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

A four-year-old girl was admitted to a paediatric clinic with a palpable lymph node and elevated alanine aminotransferase (ALT) and weak positive smooth muscle cell antibodies (SMA). Liver biopsy was never done and three months later she was referred with persistent ALT elevation. Eleven years later a dermatologist recognized spider naevi. Autoimmune hepatitis was confirmed by elevation of ALT, immunoglobulin G and positive SMA and a liver biopsy showed cirrhosis and chronic hepatitis. Children with elevated ALT at repeated measurements should be thoroughly examined if no obvious reason is present.