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Hyperkalcaemi kan vaere eneste debutsymptom ved sarkoidose
Engelsk titel: Hypercalcaemia can be the only initial symptom of sarcoidosis Läs online Författare: Hermanrud, Thorbjörn ; Janner, Julie Hjortsö ; Steffensen, Ida Elisabeth Språk: Dan Antal referenser: 5 Dokumenttyp: Fallbeskrivning UI-nummer: 14067937

Tidskrift

Ugeskrift for Laeger 2014;176(9)850-1 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Sarcoidosis is an ordinary systemic inflammatory disease that can affect many organs. It is characterized by development of non-necrotizing granulomas. It commonly affects lungs (80%) while hypercalcaemia is found in 5% and reflects an activation of T-cells within the granulomas that causes an overproduction of 1,25-dihydroxyvitamin D3. We describe a case where hyper­calcaemia was the only symptom in a patient with extra­pul­monary sarcoidosis, and the investigation was misled by different serologic findings though PET-CT showed fludeoxy­glucose uptake in the biceps femoris muscles. The diagnosis was made after a biopsy.