Sammanfattning
Aims: To compare nationwide time trends and mortality in hip and proximal humeral fractures; to
explore associations between incidences of falls risk related comorbidities (FRICs) and incidence of
fractures. Methods: The study is a retrospective cohort study using nationwide Danish administrative
registries from 2000 through 2009. Individuals aged 65 years or older who experienced a hip or a
proximal humeral fracture were included. Incidence of hip and of proximal humeral fractures,
incidence of FRICs (ischemic heart disease, COPD, dementia, depression, diabetes, heart failure,
osteoporosis, Parkinson’s disease and stroke) and incidence rate ratios (IRR) for fractures in patients
with FRICs, and all-cause mortality up to 10 years after a hip or a proximal humeral fracture were
analysed. Results: A total of 89,150 patients experienced hip fractures and 48,581 proximal humeral
fractures. From 2000 through 2009, the incidence of hip fractures per 100,000 individuals declined by
198 (787 to 589, OR = 0.75, CI: 0.72–0.80) among males and by 483 (1758 to 1275, OR = 0.74, CI:
0.72–0.77) among females. Incidences of FRICs decreased. The absolute reduction in fractures was
most pronounced for the age group above 75 years (2393 to 1884, OR = 0.81, CI: 0.78–0.83), but the
relative reduction was more pronounced in the age group of 65–75 years old (496 to 342, OR = 0.70,
CI: 0.66–0.74). IRRs for hip fractures and for proximal humeral fractures were significantly elevated in
patients with FRICs. Conclusions: The results suggest that the overall reduction in fractures can be
explained by reduction in falls related comorbidity.