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Cirkulerende tumorceller kan muligvis benyttes som prognostisk og praediktiv markör ved ventrikelcancer
Engelsk titel: Circulating tumour cells is a promising prognostic and predictive marker of gastric cancer Läs online Författare: Okholm, Cecilie ; Thorsteinsson, Morten ; Achiam, Michael Patrick Språk: Dan Antal referenser: 27 Dokumenttyp: Översikt UI-nummer: 14097273

Tidskrift

Ugeskrift for Laeger 2014;176(16)1490-3 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Despite chemotherapy and intended curative surgery, approximately 50% of patients with gastric cancer develop recurrence and eventually die of metastatic disease. The detection of circulating tumour cells (CTC) in peripheral blood is a promising prognostic and predictive marker. The most typically applied approaches to the detection of CTC are RT-PCR and immunological assays. Measurement of CTC in gastric cancer seems useful for predicting prognosis and monitoring response of chemotherapy. There is still no gold standard for CTC-detection in gastric cancer patients and larger studies are needed.