Association of mid-pregnancy antioxidative vitamin and oxidative stress levels with infant growth
during the first 3 years of life
Engelsk titel: Association of mid-pregnancy antioxidative vitamin and oxidative stress levels with infant growth
during the first 3 years of life
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Författare:
Hong, Juhee
;
Lee, Hye Ah
;
Park, Eun Ae
;
Kim, Young-Ju
;
Lee, Hwayoung
;
Park, Bo-Hyun
;
Ha, Eun-Hee
;
Kong, Kyoung Ae
;
Chang, Namsoo
;
Park, Hyesook
Email: hpark@ewha.ac.kr
Språk: Eng
Antal referenser: 33
Dokumenttyp:
Artikel
UI-nummer: 14103700
Sammanfattning
Objective: Numerous studies have revealed the impacts of maternal nutritional status on
subsequent birth outcome, but much less is known about the long-term impacts on infant growth after
birth. We investigated the association between maternal micronutrient levels/oxidative stress status
in pregnancy and infant growth during the first 3 years of life.
Design: Prospective cohort study.
Setting: The Ewha Birth & Growth Cohort study was constructed for women who had been recruited
between 24 and 28 weeks’ gestation and their offspring at Ewha Womans University Hospital.
Subjects: Maternal serum vitamin and urinary oxidative stress levels were measured, and infant
weight, height, and head circumference were measured repeatedly at birth and at 6, 12, 18, 24, and
36 months of age.
Results: Maternal vitamins A and C were positively associated with infant head circumference and
infant weight, respectively, during the first 3 years of life, even after controlling for potential
confounding factors. But, maternal oxidative stress was not related to infant growth.
Conclusions: The effects of maternal vitamin levels on subsequent infant growth during the first 3
years of life necessitate interventions to supplement antioxidative vitamins during pregnancy.