Sammanfattning
Background -The Synovitis, Acne, Pustulosis, Hyperostosis
and Osteitis syndrome (SAPHO ) is characterized by a variety
of inflammatory bone, joint and skin changes. The condition is
important for dentists, since the clinical and radiological changes
in the mandible, are similar to other inflammatory bone diseases.
Case study - A 43- year-old man was referred to the Oral and
Maxillofacial Surgery Department, Hillerød Hospital, for treatment
of severe mandibular infection. His medical history included psoriasis
and submandibular pus secretion. Orthopantomographic
evaluation revealed sequestration of the base of the mandible,
and scintigraphic bone examination showed increased uptake
in the mandible, hip and left ankle. Anaesthesia and high dose
antibiotic treatment sequestrectomy was performed, the mandible
healed uneventful and the post-operative course was without
complications.
Conclusion - A patient with bone swelling, in conjunction with
other bone pain and / or cutaneous lesions should be evaluated
both clinically, radiologically, and histologically under the tentative
diagnosis SAPHO. Aetiology is considered benign and inflammatory,
the functional prognosis for patients is good, but the treatment
is still life long.