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Oväntat hög andel förskolebarn immuna mot hepatit A-virus. Smittspårningsutredning visar på behovet av vaccination inför utlandsresor
Engelsk titel: Unexpectedly high proportion of preschool children immune to hepatitis A virus. Contact tracing investigation shows the need for vaccination prior to traveling abroad Läs online Författare: Persson, Hanna ; Nasta, Federico ; Svensson, Ingrid ; Widerström, Micael Språk: Swe Antal referenser: 19 Dokumenttyp: Artikel UI-nummer: 15017671

Tidskrift

Läkartidningen 2014;111(49-50)2224-6 ISSN 0023-7205 E-ISSN 1652-7518 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Hepatitis A (HAV) is a low incidence infectious disease in Sweden, and a majority of cases in this country are acquired abroad, although domestic cases are not uncommon in the day care setting. We investigated an outbreak of hepatitis A in two day care centres and found that a large proportion (23%) of the 113 unvaccinated preschool children were immune to HAV. This observation indicates that there may have been sub-clinical cases of HAV at the two centres. The results of our study underscore the importance of HAV vaccination in preschool children prior to travel to areas where this disease is common. The findings also highlight the need for up-to-date national seroepidemiological data on HAV immunity in different age groups in Sweden. Studies aimed at obtaining such information could also provide a basis for deciding whether targeted vaccination strategies against HAV are needed in the day care setting.