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Ventrikelcancer er den hyppigste Epstein-Barr-virus-associerede cancerform
Engelsk titel: Gastric carcinoma is the most frequent Epstein-Barr virus-associated malignancy Läs online Författare: Boysen, Trine ; Friborg, Jeppe Språk: Dan Antal referenser: 30 Dokumenttyp: Översikt UI-nummer: 15017730

Tidskrift

Ugeskrift for Laeger 2014;176(24)2264-8 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Epstein-Barr virus (EBV) is associated with 8% of gastric carcinomas (GC) worldwide, being the most frequent EBV-associated malignancy with 80,000 new cases per year. The association is based on the presence of clonal EBV products in gastric tumour cells, and elevated EBV antibodies in pre­diagnostic sera. EBV-associated GC are twice as common in males and often associated to cancer in the cardia-region. Gastric surgery increases the risk significantly. Until now, no clear interaction between Helicobacter pylori, the single most important risk factor for GC, and EBV has been established.