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Genetiske test er kommercielt tilgaengelige men inkomplette
Engelsk titel: Genetic tests are available but they are based on incomplete data Läs online Författare: Videbaek Andersen, Solvej Språk: Dan Antal referenser: 21 Dokumenttyp: Översikt UI-nummer: 15017765

Tidskrift

Ugeskrift for Laeger 2014;176(26)2454-6 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Direct-to-consumer genome-wide profiling is a rising phenomenon. The risk estimates given by these genetic tests are based on scientifically true but incomplete data. The consumers expect to be given personal individualized risk estimates for multifactorial diseases, and they are, but the risk estimates are only based on the small fraction of hereditability that we are able to explain by common genetic markers, and therefore the dimensions of other contributing factors need to be understood before one can realise the validity of a risk estimate for a multifactorial disease.