Ny lovande behandling vid ischemisk stroke. Sonotrombolys kan förstärka effekten av intravenös trombolys
Engelsk titel: Promising new treatment for acute ischemic stroke. Sonothrombolysis can enhance the effect of intravenous thrombolysis
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Författare:
Gu, Thomas
;
Wester, Per
;
Johansson, Elias
Email: Thomas.Gu@vll.se
Språk: Swe
Antal referenser: 28
Dokumenttyp:
Översikt
UI-nummer: 15037865
Sammanfattning
Intravenous thrombolysis has been a break-through for treatment of acute ischemic stroke. However, total recanalization is only
achieved in 18%. Sonothrombolysis aims at enhancing the recanalization effect by adding continuous transcranial ultrasound.
Sonothrombolysis may facilitate the recanalization rate without increased risk of intracerebral hemorrhage. This further results in
decreased risk of disability compared with only intravenous thrombolysis. Intravenously applied micro-bubbles is an additive
treatment to sonothrombolysis which might further increase the recanalization rate but perhaps at the expense of increased risk of
intracerebral hemorrhage. In a case-series at Umeå Stroke Center, we report the results of the first 20 ischemic stroke patients
treated with sonothrombolysis in Sweden. Our initial results look promising with recanalization rates similar to earlier published data.
No intracerebral hemorrhage occurred among our sonothrombolysed patients.